Whatman Anotop Plus non-sterile syringe filters from Cytiva have an integrated glass microfiber prefilter and inorganic membrane, enabling filtration of a wide variety of sample solvents and compounds. Capillary pore structure for well-defined particle filtration Low protein binding filter for applications requiring high protein recovery Integrated glass microfiber prefilter for filtering larger volumes of difficult-to-filter samples Recyclable after use. Learn how you can recycle it. Cytiva's business also offers sterile Anotop Plus syringe filters. Anotop Plus syringe filters for challenging samples High solid content samples can be difficult to filter because of their tendency to prematurely clog a single membrane filter. Each Anotop Plus syringe filter includes a glass prefilter designed to separate difficult, hard-to-filter samples without adversely affecting the filtration efficiency of the final membrane. Inclusion of a prefilter can eliminate the need for expensive and time-consuming sequential filtration. Whatman Anotop Plus filters can be used with most organic solvents and aqueous materials and are suitable for sample volumes up to 100 ml. They come in two diameters and three pore sizes. Applications for filters with integrated prefilter Common applications for Anotop Plus syringe filters include sample preparation prior to capillary electrophoresis or HPLC/UHPLC, as well as filtration of nanoparticles.